Building the Molecular Foundation for Life Sciences and Pharmaceutical Innovation Through Verifiable Synthesis Quality
Gene Synthesis · Oligonucleotide Synthesis · Plasmid Vector Construction · In-House Developed Molecular Reagents · 50,000+ Ready-to-Ship Genes
Precision in Synthesis · Innovation for the Future
1. About ZhiYin Biotech
Founded in December 2025, Shanghai ZhiYin Biotechnology Co., Ltd. is located in the core area of Zhangjiang High-Tech Park, Shanghai (Building 6, No. 688 Kangqiao East Road, Pudong New Area, Shanghai). The company is a technology-driven enterprise specializing in molecular and synthetic biology.
With gene synthesis, oligonucleotide synthesis, and plasmid vector construction as its core technical services, the company also independently develops molecular biology reagents and has established a large-scale inventory of ready-to-ship genes. Together, these capabilities form an integrated business platform built on three pillars: technical services, proprietary products, and ready-to-ship inventory, providing efficient, reliable, and comprehensive one-stop support for life science research and innovative drug development.
From sequence design and optimization to transfection-ready plasmids, ZhiYin Biotech is committed to transforming research delays into tangible results through predictable delivery timelines and verifiable synthesis quality.
2. Our Integrated Three-Pillar Business Platform
1. Technical Services: Comprehensive Expertise in Molecular Construction
Covering the entire workflow of nucleic acid synthesis, construction, and validation, we provide standardized and customized services, including gene synthesis, DNA fragment synthesis, cDNA/ORF cloning, shRNA/gRNA vector construction, molecular cloning and mutagenesis, and plasmid DNA extraction. Our services support a wide range of vector requirements, from prokaryotic and mammalian expression systems to specialized expression platforms.
2. Proprietary Products: Reliable Tools for Every Experimental Step
Drawing on our extensive laboratory experience and technical service applications, we continuously refine our product portfolio. We have developed a series of molecular biology reagents covering three essential experimental processes: nucleic acid electrophoresis, nucleic acid purification, and cell transfection. These products support both our internal service delivery and the research needs of academic laboratories and biotechnology companies.
3. Ready-to-Ship Inventory: Saving Valuable Research Time
We have established a ready-to-use gene library containing over 50,000 gene constructs and a vector library with more than 200 vector resources. Frequently requested genes have been pre-cloned into expression vectors, enabling precise searches, flexible selection, and immediate ordering. This significantly reduces traditional lead times from weeks to rapid shipment directly from stock.
3. Core Technical Services
1. Oligonucleotide Synthesis
Supporting both RNA interference (RNAi) and RNA activation (RNAa) technologies, we provide siRNA synthesis, modified and customized siRNA synthesis, saRNA synthesis, microRNA synthesis, miRNA mimic/inhibitor synthesis, and agomir/antagomir synthesis. Our integrated workflow covers target evaluation, intelligent sequence design, chemical synthesis and modification, and quality validation.
2. Gene Synthesis and DNA Fragment Synthesis
We provide integrated services ranging from sequence design and codon optimization to full-length gene synthesis. Our capabilities include the synthesis of challenging DNA sequences featuring high GC content, repetitive regions, and complex secondary structures. We also support short DNA fragment and primer-level synthesis to accommodate flexible requirements across different stages of research.
3. Plasmid Vector Construction and Modification
Our comprehensive services include cDNA/ORF cloning, shRNA/gRNA vector construction, molecular cloning and mutagenesis (site-directed mutagenesis, fragment insertion and deletion, and seamless cloning), as well as plasmid DNA extraction. Combined with dual-luciferase reporter assays, we can provide functional validation of constructed vectors, ensuring that our deliverables are not merely plasmids, but reliable tools ready for downstream applications.
4. In-House Developed Molecular Biology Reagents
Our major products include the ZY RulerStar DNA Marker Series (1kb-IV, 100bp-II Plus, 250bp-I, and 250bp-II), GelRed Pre-Stained Loading Buffer, ZY GelStar Gel Extraction Kit, ZY PurePrep Plasmid Miniprep Kit, Seamless Cloning Kit, and ZY FectEasy DNA/RNA Transfection Reagent.
4. Our Resource Platform: 50,000+ Ready-to-Ship Genes and 200+ Diverse Vectors
Ready-to-Ship Gene Library: Over 50,000 ready-to-use gene constructs covering diverse vector systems. Our library supports precise searching, flexible selection, and immediate ordering. Genes are pre-cloned into expression vectors and ready for downstream experiments.
Diverse Vector Library: More than 200 vectors covering prokaryotic, mammalian, and specialized expression systems. With comprehensive functions and a wide variety of tags, our vectors support research applications including gene expression, gene knockdown, genome editing, and reporter assays.
Ready-to-ship plasmids are available with clearly defined specifications and transparent pricing. Standard pricing is based on gene fragment length and plasmid DNA quantity, ensuring consistent and predictable delivery standards.
5. Corporate Culture
Corporate Spirit
Rigorous and pragmatic, collaborative and accountable, persistent in continuous improvement.
Corporate Vision
To become a driving force in advancing gene synthesis technology, making precise and efficient molecular construction services accessible to every life science exploration and pharmaceutical innovation.
Corporate Mission
To build a solid molecular foundation for life science research and pharmaceutical innovation through verifiable synthesis quality and a dependable service system.
Service Philosophy
Responsive to every need, transparent throughout every process, and committed to reliable results.
6. A Service System You Can Rely On
ZhiYin Biotech puts its service philosophy into practice at every stage of each project. Responsive to Every Need — Our technical engineers directly communicate with customers regarding target evaluation, sequence design, and project planning, providing well-defined solutions and transparent quotations. Transparent Throughout Every Process — Project progress is communicated at key milestones, and any unexpected issues are promptly reported. Committed to Reliable Results — Sequencing and quality verification are completed before delivery, with clearly defined delivery standards and traceable documentation.
7. Applications
ZhiYin Biotech's services and products are widely applicable to gene function and signaling pathway studies, non-coding RNA mechanism research at universities and research institutes, target discovery and early-stage validation in innovative pharmaceutical companies, antibody and recombinant protein expression and construction, as well as tool development in in vitro diagnostics and synthetic biology. Whether supporting individual research projects or large-scale R&D programs, our integrated platform enables efficient coordination and comprehensive technical support.